CADASIL

CADASIL stands for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy and is a genetic disease characterised by migraines with aura, cerebrovascular disease causing dementia and stroke. The disease is caused by a mutation of the NOTCH3 gene. Some patients also experience epilepsy.

CADASIL has only recently been discovered and only around 400 families with the disease have been diagnosed. However, it is believed that the disease is far more prevalent than current diagnoses indicate.

Links

• CADASIL Patient Site