Christof Koch (born November 13, 1956) is an American neuroscientist. He currently holds the position of Lois and Victor Troendle Professor of Cognitive and Behavioral Biology, California Institute of Technology. He is the executive officer of the Computation and Neural Systems program at Caltech.
In addition to a number of edited books he has published two monographs: Biophysics of computation: information processing in single neurons (1999), and more recently The quest for consciousness: a neurobiological approach (2004).
He has been active since the early 1990s in the promotion of consciousness as a scientifically tractable problem, and has been particularly influencial in arguing that consciousness can now be approached using the modern tools of neurobiology. His primary collaborator in this endeavour was the late Francis Crick. He is the local organiser of the 2005 meeting of the Association for the Scientific Study of Consciousness .