Cleopatra is the name given to several historical and mythological figures, most especially:
- Cleopatra VII of Egypt, last of the Ptolemaic rulers of Egypt, lover of Roman leaders Julius Caesar and Mark Antony, and the subject of several plays (including one by Shakespeare) and various films.
- Six other Egyptian queens: Cleopatra I, Cleopatra II, Cleopatra III , Cleopatra IV , Cleopatra V and Cleopatra VI.
- The sister of Alexander the Great, see Cleopatra, sister of Alexander
- Cleopatra Selene, daughter of Antony and Cleopatra
- Daughter of Idas and wife of Meleager in Greek mythology
- See Cleopatra (movie) for movies based on the life of Cleopatra of Egypt
- Cleopatra is a musical group from the UK who had several hits in the 1990s.
- Cleopatra is a musical group from Greece who entered the Eurovision Song Contest 1992 with the song "Olou Tou Kosmou I Elpida"
See Cleo for people, places, and things named Cleo.