Ergine, also known as d-lysergic acid amide, LSA, and LA-111, is an alkaloid of the ergoline family that occurs in various species of vines of the Convolvulaceae and some species of fungi. As the dominant alkaloid in the hallucinogenic seeds of Rivea corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian baby woodrose) and Ipomoea violacea (tlitliltzin), it is often stated that ergine and/or isoergine (its optical isomer) is responsible for the hallucinogenic activity. In fact, the effects of synthetic ergine and isoergine are not particularly hallucinogenic, see Mixing the Kykeon below for a summary of human trials, and Chapter 17 and entry #26 of TiHKAL for further discussion. Whether or not these compounds account for the hallucinogenic effects of the seeds remains unclear. Ergine is a DEA schedule III drug in the United States.
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