Evans syndrome

Evans syndrome is a combination of idiopathic thrombocytopenia and autoimmune hemolytic anemia. Treatment includes intravenous immunoglobulin (IVIg) and steroids with or without transfusion of platelets and/or red blood cells.

This is primarily a disease of children age 5 to 10. The cause is not known. It is usually treatment-resistant requiring long term or periodic steroid use.

Reference

• Evans RS, Takahashi K, Duane RT, Payne R, Liu C. Primary thrombocytopenic purpura and acquired hemolytic anemia; evidence for a common etiology.

Arch Intern Med 1951;87:48-65. PMID 14782741.