Gemzar

Gemzar is the brand name of the antineoplastic drug which Eli Lilly and Company developed. Pharmacologic ingredient is Gemcitabine and this is Nucleoside which replaced the hydrogen of 2' grades of deoxyribose of deoxycytidine by fluoride.

• chemistry name:2'-Deoxy-2',2'-difluorocytidine monohydrochloride
• generic name:GemcitabineHydrochloride
• mol. formula:C9H11F2N3O4・HCl
• mol. weight:299.66
• CAS No.122111-03-9
• melting point:287-292°C
• boiling point:N/D
• pH:3
• Appearance:White to off white solid

Medical description

Adjustment

Non-small-cell lung cancer, pancreatic cancer, and breast cancer

The action machine beginning

DNA chain is extending stopped by another one nucleoside's being taken into DNA chain as much as cytidine, and adhering to DNA. Apoptosis is induced by this, and the tumor cell is driven in to the suicide.

link

• Eli Lilly and Company
• Lilly Oncology
• Gemzar