Menstrual cramp

Menstrual cramps are spasmodic pains felt in the low abdomen, lower back and the upper thighs during the bleeding phase of a woman's menstrual period.

They are thought to be caused by the release of prostaglandins and other inflammatory mediators in the uterus (womb). The symptoms can be so severe as to cause diarrhoea, vomiting and general malaise. Drugs which inhibit the production of prostaglandins, such as the non-steroidal anti-inflammatories (NSAIDs) Naproxen, Ibuprofen and Mefenamic Acid, can provide relief.