Frederick Octavius Pickard-Cambridge (November 3, 1828 - March 9, 1917) was an English clergyman and zoologist.
Pickard-Cambridge was born in Bloxworth rectory, Dorset. He studied theology at the University of Durham, and became a vicar in 1858, succeeding his father at Bloxworth in 1868.
His main interest was in birds and spiders, becoming interested in the latter after a meeting with John Blackwall in about 1854. He became a world authority on spiders, describing a considerable number of new species.
He became a Fellow of the Royal Society on September 9, 1887.