The Second Deakin Ministry was the fifth Australian Commonwealth ministry, and ran from 5 July 1905 to 12 December 1906.
Protectionist Party
- Hon Alfred Deakin, MP: Prime Minister and Minister for External Affairs
- Hon Isaac Isaacs, KC MP: Attorney-General (to 12 October 1906)
- Hon Sir William Lyne, KCMG MP: Minister for Trade and Customs
- Rt Hon Sir John Forrest, GCMG MP: Treasurer
- Hon Austin Chapman, MP: Postmaster-General
- Senator Hon Thomas Playford: Minister for Defence
- Hon Littleton Groom , MP: Minister for Home Affairs (to 12 October 1906), Attorney-General (from 12 October 1906)
- Hon Thomas Ewing , MP: Vice-President of the Executive Council (to 12 October 1906), Minister for Home Affairs (from 12 October 1906)
- Senator Hon John Keating : Minister without portfolio (to 12 October 1906), Vice-President of the Executive Council (from 12 October 1906)
- Hon Samuel Mauger : Minister without portfolio (from 12 October 1906)